Plant growth, far more than metazoan growth, is intricately linked to nutrient sensing. In plants, nutrients and stress affect not only the growth rate but also the number of organs produced and the timing of developmental transitions. Given the considerable information about TOR in yeast and mammalian systems, the obvious question for the plant researcher becomes, "how much of this is relevant to plant growth regulation"? Put another way, "how has this ancestral eukaryotic nutrient-sensing mechanism adapted, if at all, to mediate plants' meristem-driven growth"?
To address this question, plant biologists have relied on four tools: bioin-formatics, rapamycin, biochemistry, and genetics. For the remainder of this work I will survey the progress made toward understanding TOR signaling in plants using each of these tools.
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