Steven D. Clouse
Department of Horticultural Science, North Carolina State University,
Raleigh, NC 27695-7609, USA
Abstract Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require membrane-localized receptor kinases for BR perception and signal transduction. Recent biochemical and genetic analyses have demonstrated that these plant proteins share many features of the general paradigm of animal receptor ki-nase function, including ligand-dependent heterodimerization and phosphorylation on specific residues of the cytoplasmic kinase domain. These studies have enhanced our understanding of early events in BR signaling as well as general modes of action for plant receptor kinases. Detailed studies of downstream events in BR signal transduction have now clarified nuclear events associated with the terminal end of BR signaling and have provided novel mechanisms of BR-regulated gene expression. This chapter summarizes the current status of BR signaling knowledge, focusing on these recent developments.
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