Actin

Actin was discovered nearly half a century ago and purified from skeletal muscle its abundance and the ease of isolation have made rabbit muscle a-actin isoform the protein of choice for most biochemical studies. There are, however, obvious reasons for studying the physico-chemical properties of actin isolated from different tissues and other organisms. Indeed, actin isovariants from non-skeletal muscle tissues have distinct biochemical properties (Sheterline etal., 1998), and actins from...