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Nutritional Treatments For Glaucoma

The conventional approach to managing glaucoma includes a proper referral to an ophthalmologic surgeon for a thorough evaluation. When surgical intervention an iridotomy is performed, the majority of patients will be totally cured and have no visual loss.30 However, when surgery is performed, there are potential risks that must be weighed. Specific adjuvant ACM modality management may include the use of nutrients and herbs to strengthen the vasculature of the eye and provide antioxidant protection. Homeopathy may be effective for acute pain relief. Regular aerobic exercise may also be helpful for treating the condition.31,32 Dietary changes that may be influential in preventing the progression and occurrence of glaucoma, as well as hastening recovery from iridotomy include reducing or eliminating exposure to allergens that produce altered vascular permeability and increased intraocular pressure. All known food allergens should be eliminated. In addition, it is important to reduce...

Botanical Agents For Treating Glaucoma

Several botanical agents have been shown to be helpful for managing glaucoma. These include Vaccinium myrtillus (limited research) 47 Crataegus monogyna (hawthorn berries), especially Additional interest has been directed toward Coleus forskoliin. The triterpene forskoliin from the plant stimulates the enzyme adenylate cyclase.50 Adenylate cyclase then stimulates the ciliary epithelium to produce cyclic adenosine monophosphate (cAMP). This cascade then leads toward reducing aqueous humor inflow and decreasing intraocular pressure. A clinical study on the topical use of forskoliin has been promising in healthy human subjects, but use for patients with glaucoma has historically been lacking. What is more, while oral standardized extracts of Coleus forskoliin are known to raise cAMP, it is not clear if oral dosages have any effect on cAMP levels in the eye. As such, more research is needed. Regardless of the medical armamentarium enlisted to treat glaucoma, prevention of this is...

Botanical Treatments For Cataracts

Botanical agents that may be helpful for treating and managing cataracts include Vaccinium myrtillus (bilberry), a close relative of blueberry, which is high in bioflavonoid complex anthocyanosides.26 Anthocyanosides have been shown to protect both the lens and the retina from oxidative damage. Bilberry also helps patients to adapt to bright light, but research on effects on night vision have produced mixed results. Pulsatilla pratensis (pulsatilla) has historically been used internally for the treatment of senile cataracts however, careful attention must be used when prescribing this toxic herb. Cineraria maritime (silver ragwort) has been used in the form of eye drops for treating patients who are in the early stages of senile cataracts but, note that use of this herb is contraindicated for patients with glaucoma.27 GLAUCOMA DESCRIPTION AND ETIOLOGY Glaucoma is the second leading cause of blindness in the United States. The term glaucoma describes a group of eye conditions involving...

Quantitative Description of Mass Transfer

In the majority of cases, water and solutes cross cuticles by diffusion, which is based on random molecular motions over small molecular distances. Quantitative description of diffusion involves a mathematic model based on fundamental physical properties. This kind of approach is not very popular with many biologists, who when confronted to Fick's law of diffusion are tempted to change the subject. However, Fick, one of the pioneers in diffusion, was a biologist, more precisely a physiologist, who among other things worked on astigmatism of the eye, functioning of muscles and thermal functioning of the human body (quoted from Cussler 1984).

Alternative And Complementary Approaches To Treating Common Ocular Disorders

Cataracts, Glaucoma, Retinopathy, and Macular Degeneration It has been said that the eye is the ''window'' to a person's soul. For the physician, the eye is a window to a person's body. The eye provides a direct view of blood vessels and nerves and can reflect the state of a person's overall health. The eye can also be affected by conditions within the body. This chapter examines four common eye disorders cataracts, glaucoma, diabetic retinopathy, and macular degeneration and discusses alternative and complementary medicine (ACM) approaches to treating these disorders. The etiologies and clinical presentation for each disorder are described and then popular ACM interventions are outlined. CATARACTS DESCRIPTION AND ETIOLOGY Cataracts, the clouding and opacification of the crystalline lenses of the eyes,1 are the leading cause of decreased vision and blindness in the United States. It is estimated that 20.5 million (17.2 ) Americans older than 40 years have cataracts in either eye....

Health aspects of carotenoids

In human nutrition, carotenoids play an important role as a source of provitamin A. In the gastrointestinal tract 3-carotene gets converted to vitamin A, which plays an important role in the regulation of vision, growth and reproduction (Ong and Choo, 1997). More recently, however, the protective effects of carotenoids against serious disorders such as cancer (Peto et al., 1981 Shekelle et al., 1981), heart disease, squamous cell carcinoma of the lung, oral tumours and degenerative eye disease have been recognized, and have stimulated intensive research into the role of carotenoids as antioxidants and as regulators of the immune response system. The antioxidant property of 3-carotene by its effective radical trapping was studied by Burton and Ingold (1984). Kunert and Tappel (1983) reported the efficient reduction of lipid peroxidation by prior treatment with 3-carotene in guinea pigs.

South And Central America

An infusion of the leaf of this plant, known as 'core-core', is used in Chile by the Mapuche Amerindians to treat cataract, shock and fever. The root, considered astringent, was used to treat toothache and the whole plant used as an antiinflammatory agent (Rodriguez etal., 1994). It is not normally used for diabetes, but the hypoglycaemic effects of an extract of the whole plant was assessed in normoglycaemic and alloxan diabetic rats and the activity found to be significant, but less than that produced by tolbutamide (Rodriguez etal., 1994).

Phyla nodiflora L Greene

Phyla Nodiflora

60-70 g of fresh leaves and 8-10 g of black pepper are ground daily for 8-10 min 1 cup (250 mL) of water is also added. Then it is filtered with a cloth and given to patients suffering from skin diseases, mouth sores, earaches, toothaches, eye diseases (phora), general body inflammation, and piles also used to purify blood. For children, 2-3 tsp (15-20 mL) of drug (at one time) is given once daily, in the morning, for 5-6 days. For adults, 1 cup (250 mL) of drug (at one time) is given once daily, before breakfast, for 10-15 days. Skin disease, pimples, lesions, mouth sores, piles, earaches, toothaches, body inflammation, and eye diseases (phora) also used to purify blood.

Traditional medicinal uses

Wedelolactone Structure

India According to Ayurvedic philosophy E.alba is bitter alterative and anthelmintic. It is useful in inflammations, hernia, eye diseases, bronchitis, asthma, leucoderma, anemia, heart and skin diseases, night blindness, syphilis etc. It is reported to be beneficial for the complexion, hair, eyes, and teeth. Expressed juice of E. alba mixed with goat's milk is used in frontal sinusitis and nasal cattarh in children. Bhringraj taila and Bhringrajadi churana are official preparations.

Amaranthus viridis Linn

Of dried fruit of Ficus carica, and 150 g of sugar are mixed and ground together for 5-7 min. This powder-like material is then stored in a plastic or glass bottle and given to patients suffering from vision problems. For children, not used. For adults, 2-3 tsp (15-20 g) of powdered drug (at one time) is given with 1 cup (250 mL) of water twice daily Disease Cured To improve eyesight.

Zizyphus oxyphylla Edgew

2-3 times, and cut into small 2-3-in. pieces. They are boiled in 5-6 L of water for 1-2 h. When 1 liter of water is left, it is filtered with a cloth, stored in a glass bottle, and given to patients suffering from mouth sores, skin diseases, pimples, skin lesions, earache, eye diseases, and high blood pressure. For children, earache, eye diseases, and high blood pressure.

Ajuga bracteosa Wall ex Benth

150 g of fresh plant material is ground daily for 5-6 min and 1 cup (250 mL) of water is added. This mixture is filtered with cloth and given to patients suffering from blood diseases, mouth sores, earache, eye diseases, pimples, skin lesions, throat pain, and body inflammation. For children, cup of extract (at one time) is given once daily before breakfast for 4-5 days. For adults, 1-2 cups (250-500 mL) of the drug (at one time) is given once daily before breakfast for 10-15 days. Mouth sores, throat pain, blood purification, body inflammation, earache, eye diseases, skin lesions, and pimples.

Section C 2 Angiosperms Dicots 341 Acacia catechu LF Wild

Medicinal Uses Acacia

4-5 g of kath is dissolved in 2-3 tsp (15-20 mL) of water and given to patients, especially children (5-15 years old), suffering from mouth sores, diarrhea, earache, sore throat, and eye diseases, 2-3 times per day for 3-4 days. Mouth sores, sore throat, diarrhea, earache, and eye diseases.

Resin Glycosides 2017

Semisynthetic Derivatives of Tropane Alkaloids. Generally semisynthetic remedies are developed with the aim to improve the pharmacodynamic and or pharma-cokinetic properties of a natural agent. Homatropine (3a-mandeloyloxytropane) (Fig. 3.25) is a shorter acting mydriatic in contrast to atropine which is of advantage in diagnostic ophthalmology. It can be synthesized by acylation of 3a-hydroxytro-pane and represents one of the oldest semisynthetic drugs at all. A century ago, Jowett and Pyman (1909) continued with structure activity relationship studies of tropanes by checking a series of semisynthetic 3a-acyloxytropanes (tropeines). They found out that certain derivatives possessed more or less marked mydriatic properties in contrast to others most of them were less active than homatropine. Today, semisyn-thetic quaternary ammonium substitutes of atropine such as ipratropium bromide and of scopolamine such as oxitropium bromide and N-butylscopolaminium bromide (Fig. 3.26) play an...

Early traditional medicine

Other uses are just empirical, for example those based on the 'Law of Signatures'. This is an old belief which says that nature has provided a plant for every disease and has indicated by an obvious sign for which disease or which part of the body each drug plant is to be used. Thus the shape of a plant or of one of its components may suggest a cure. This belief existed in many parts of the world, including Europe in the Middle Ages. The classical example was a walnut, which having the shape of a brain, should thus be used for diseases affecting the brain. Grier (1937) cites other examples 'Plants with red flowers were to be used in blood disorders and those with yellow flowers, also turmeric, in jaundice. Saxifrages, which grow on rocks and break them up, would be useful for stones in the bladder, a belief in the Middle Ages in England (Grier, 1937). Euphrasia was to be given in eye diseases, because a black spot in the flower resembles the pupil of the eye.' Similar beliefs are...

Morten Sandergaard

Steemann (Fig. 1.1) began his academic career as a botanist and specialised in phytoplankton taxonomy. At the age of 21 he became a member of the Dana round-the-world expedition 1928-1930 and his doctoral thesis at the age of 27 was on the genus Ceratium in the South Pacific (see appendix reference 6). His publications from the 1930s show that at this time he had developed an interest in quantitative ecology and specifically plankton production and the relationship between phyto-plankton and zooplankton (see appendix references 2, 5, 8, 11, 12). His second scientific paper published in 1932 was on plankton production. Problems with his eyesight forced him to give up the many hours at the microscope and he changed, in his own words, 'to an experimental biologist', where marine primary production, plant physiology and specifically photosynthesis, light adaptation and inorganic carbon assimilation became his 'pet areas'.

Lipoic Acid

A study was performed in individuals with symptomatic diabetic polyneuropathy and oral ALA supplementation. The results indicated that oral ALA in doses of 600 mg, 1,200 mg, and 1,800 mg per day was effective in reducing neuropathic symptoms of diabetic distal symmetric polyneuropathy at five weeks evaluation.58 In addition, studies using diabetic rats have shown that oral supplementation with dihydrolipoic acid, the reduced form of ALA, delayed the development and progression of cataract in these rats.59


L The berries are used in India in the treatment of fever, diarrhoea and eye diseases (Chopra et al., 1956). In Nigeria a decoction of the leaves is said to be diuretic and laxative and that of the young shoots is given in the treatment of psoriasis and skin disease (Dalziel, 1937).


Late in the twentieth century in the United States, the legal use of marijuana has been promoted because of its potential for treating several medical conditions, including glaucoma (high fluid pressure within the eye), spasticity, and nausea during chemotherapy. Several states, most notably California, have passed compassionate use laws that allow patients to legally obtain marijuana for smoking. At the same time, several states are moving forward with legislation to allow fiber hemp to be grown legally, though these efforts will require the cooperation of the U.S. Drug Enforcement Administration. Currently, hemp fiber for use in the United States is imported from Canada, China, and several other countries where it is grown legally. see also Cultivar Defenses, Chemical Fiber and Fiber Products Psychoactive Plants.

CII3CI Icilj

Pilocarpus microphyllus is currently the main source. The alkaloid content (0.5-1.0 ) consists principally of the imidazole alkaloid pilocarpine together with small amounts of pilosine (Fig. 5.69). Pilocarpine salts are valuable in ophthalmic practice and are used in eyedrops as miotics and for the treatment of glaucoma. Pilocarpine is a cholinergic agent and stimulates the muscarinic receptors in the eye, causing constriction of the pupil and enhancement of outflow of aqueous humour.

Mountain bog

Species composition varies from bog to bog, reflecting differences in elevation, topography, hydrology, underlying rock, and recent land-use history. Three distinct types of bog are described southern Appalachian bog, the swamp forest-bog complex, and cataract bogs. Bogs are technically known as fens, though they are commonly called bogs, a term that is retained here. CATARACT BOG Bogs are more common in the northern Appalachians than the southern Appalachians, largely because receding glaciers scoured out basins favorable for bog development in the north but not in the south. The swamp forest-bog complex is scattered throughout the Appalachians from Pennsylvania to Georgia, but the Southern Appalachian bog type is largely restricted to Virginia and North Carolina, mostly at mid- to high elevations. Cataract bogs are rare, known only from South Carolina other locations are likely but have yet to be documented.

Melia azedarach Linn

Palladia Campestris Medicinal Benefits

In 3 cups (750 mL) of water for 15-20 min. When 1 cup (250 mL) of water is left, it is strained with a cloth or filtration pot. This decoction is given to patients suffering from eye diseases (eyesore) and malarial fever. For children, 1 tsp (5 mL) of decoction (at one time) is mixed in 1 cup of water, 5-6 g of salt is also added, and then the mixture is given to the patient 2-3 times per day for 6-7 days. For adults, 2-3 tsp (15-20 mL) of decoction (at one time) is mixed in 1 cup (250 mL) of water, 8-10 g of salt is also added, and the mixture is given 2-3 times per day for 8-10 days. (b) 75 g of dry fruit of Melia azadarach, 125 g dry fruit of Phyllanthus emblica (Amla), and 125 g of Terminalea chebula (Harir) are ground together for 10-15 min. Then 25-30 tablets (each 5-6 g) are made from this powder and stored in a plastic or glass bottle for further use. These tablets are given to patients suffering from piles, and to purify the blood. For children, not used. For adults, one...

Oriental Medicine

G. thunberghii, known as 'Gen-no-shoko' in Japanese, is used in Kampo (traditional Japanese medicine) particularly as a remedy for diarrhoea induced by inflammation of the small intestine and also for liver and haematological disorders (Kimura et al., 1984). It also has been used to treat cataract (Fukaya etal., 1988). The biological activity is usually ascribed to the tannin content, particularly geraniin. Extracts of the plant have been shown to reduce gastro-intestinal motility in isolated rat intestine (Kan and Taniyama, 1992) have inhibitory effects on cholera toxin-induced secretion from rat gastric mucosa and other astringent effects (Ofuji etal., 1998), giving support to the traditional usage of Geranium for diarrhoea. They also exhibit strong antimutagenic effects against direct acting mutagens (Okuda et al, 1984). Like other tannin-containing drugs, extracts reduced levels of ureamic toxins, including creatinine, methyl-guanidine and guanidinosuccinic acid, in rats with...

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