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N-acetyl-carnitine is also thought to have neuroprotective effects, assisting the serotonin neurotransmitter pathways, enhancing transmission of nerve impulses in the brain, and decreasing loss of age-related glucocorticoid receptors in the hippocampus. In conditions of compromised cerebrovascular blood flow, N-acetyl-carnitine may increase blood flow to the brain in patients with cerebrovascular disease.31 N-acetyl-carnitine is also beneficial for people with vascular dementia and those who are recovering from strokes.32 This amino acid has improved cerebral blood flow in people with chronic brain ischemia after only one dose.33 The supplement can improve memory and visual-spatial orientation skills in individuals with cognitive impairment who are recovering from alcohol dependency.34 Similarly, N-acetyl-carnitine may improve cognitive function and memory in people with age-related cognitive decline and memory impairment.35 Much research has been done, using this compound, to help people with Alzheimer's disease, which is marked by a significant decrease in acetylcholine and cholinergic neurons.36

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