There is conflicting evidence regarding the role that Helicobacter pylori may play in GERD pathology. There are various studies that have looked at treatment of gastritis by eradicating H. pylori and the effects of treatment on concurrent GERD symptoms. The results of these studies vary from showing improvement to showing worsening of GERD symptoms.18 Research regarding inflammation in the gastroesophageal junction, or cardia, has indicated that the presence of erosive GERD or H. pylori gastritis is associated with the inflammation.19 In addition, GERD and carditis are associated with intestinal metaplasia at the gastroesophageal junction.20

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