Beefsteak Plant

The beefsteak plant (Perilla frutescens) contains several active ingredients such as rosmarinic acid and luteolin. Rosmarinic acid is a plant polyphenol found in the Lamiaceae genus of plants, which includes basil (Ocimum spp.), sage (Salvia officinalis), mint (Mentha spp.), rosemary (Rosmarinus officinalis), and perilla leaf.56 Oral supplementation using perilla leaves or extracts of rosmarinic acid has been shown to suppress allergic reactions.57,58 A study confirmed that oral administration of perilla leaf extract inhibits production of TNF-alpha and decreases the allergic response and inflammation in mice.59 Another study demonstrated

Figure 5-4. Rosemary (Rosmarinus officinalis).

Figure 5-4. Rosemary (Rosmarinus officinalis).

that perilla leaf extract enriched with rosmarinic acid is an effective treatment for patients who have seasonal allergic rhinoconjunctivitis.58 Like rosmarinic acid, luteolin—found in various species of the perilla plant—is another plant flavonoid that has potent antiallergic properties.59

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