Application of Dynamic Flux Analysis in Plant Metabolic Networks

Morgan, Natalia Dudareva, and David Rhodes Metabolic networks are composed of metabolic pathways that consist of biochemical reaction steps. The functionality of pathways within a network is determined by metabolic fluxes, defined as the amount of converted metabolite per unit of time, per cell (or per unit mass of tissue), through each biochemical step within a metabolic pathway. The flux through a pathway depends on the kinetic properties of enzymes, as well as on...

Application of Genome Scale Models

Despite the large number of genome sequences available, only a handful of genome-scale metabolic models have been completed to date (Table 8.2). Some of these organisms are industrially important, such as E. coli, L. lactis, S. cerevisiae, S. coelicolor, and L. plantarum, and these models can be used to optimize the productivity of natural products. Others are human pathogens, such as H. influenzae, Table 8. 2 List of organisms with genome-scale metabolic models. If multiple versions exist,...

Contributors

Allen Department of Plant Biology, Michigan State University, East Lansing, MI 48824, USA Diane M. Beckles Department of Plant Sciences, University of California, Mail Stop 3, 133 Asmundson Hall, One Shields Avenue, Davis, CA 95616, USA Nanette R. Boyle School of Chemical Engineering, Purdue University, 480 Stadium Mall Dr., West Lafayette, IN 47907, USA Amy J.M. Colon Department of Horticulture, Purdue University, West Lafayette, IN, USA Natalia Dudareva Department of Horticulture and...

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Metabonomics Schematic

22 11 103 48 79 83 81 of statistical methods, selecting or discarding certain subsets based on specific criteria, or other mathematical methods. In applying statistics to a scientific problem, one begins with a biological process or sets of organisms to be studied. This might be a population of transgenic plants compared to untransformed wild type, plants treated with a specific stress elicitor compared to unstressed plants, or plants growing in one environment vs. another. It may instead be a...