Hydroxycoumarins

Hydroxycoumarins represents another group of coumarins (Figs. 5.258, 5.259 ), which are widely distributed in Apiaceae and Gramineae. They are found in Aesculus hippocastanum, Angelica pubescens, Artemisia lactiflora and Crategeus oxycantha. Callophylloide and jacareubin coumarins derived from Calophyllum inophyllum have antiarrhythmic, coronary vasodilator, anticoagulant, anti-inflammatory and antiarthritic and gastro protective activites, respectively. Calophyllum apetalum contains coumarin named aperalolide.

Fig. 5.258 Structure of coumarin.

Fig. 5.258 Structure of coumarin.

Aesculetin Herniarin

Fig. 5.259 Structure of common hydroxycoumarins.

Aesculetin Herniarin

Fig. 5.259 Structure of common hydroxycoumarins.

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