R

5a; R1 = CH3; R2 = OCH3; R3 = H 5b; R1 = CH3; R2 = OH; R3 = H 5c; R1 = R3 = H; R3 = OCH3 5d; R1 = CH3; R2 = R3 = H 5e; R1 = CH3; R2 = R3 = OCH3

Hexahydrocurcumin D emethylated hexahydrocurcumin Demethylated hexahydrocurcumin Demethoxylated hexahydrocurcumin Methoxylated hexahydrocurcumin

7a; R1 = R3 = OCH3; R2 = H (3R , 5S ) 7b; R1 = R2 = R3 = OCH3 (rel. RS )

7d; R1 = OCH3; R2 = H; R3 = OH (rel. RS ) 7e; R1 = R3 = OH; R2 = H (3S, 5S )

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